Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.

3,3'-Bi[1H-indole] 是一种源自诺卡氏菌 (Nocardiopsis sp.) 的海洋天然产物。

Saikosaponin C 通过抑制 caspase-3 激活和 caspase-3 介导的 FAK 降解，有效抑制 LPS 诱导的细胞凋亡。